*Unfortunately, Prolific has followed Microsoft's recommendations about the Registry and is now putting a copy of the settings into \HKEY_USERS\ which has a randomly generated UID, which means I cannot write an effective Registry Cleaner for MA2!!!
On my Windows ME system anything that goes into \HKEY_CURRENT_USER\ is automatically copied to \HKEY_USERS\. Even Fish Picker does that somehow, although I only instruct it to write in \HKEY_CURRENT_USER\.
So if you point your regcleaner to \HKEY_CURRENT_USER\ it cleans \HKEY_USERS\ as well. Not sure how that works on Windows 2000 or XP, but I imagine it would at least work for the user running the regcleaner.